Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183813 | 0.85 | ALDH1A1 (0.52) | HTTALDH1A1AKR1C3MAPK1L3MBTL1 | |
| SCHEMBL10490780 | 0.82 | KMT2A (0.59) | HTTALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL3048489 | 0.82 | ALDH1A1 (0.57) | HTTALDH1A1MAPK1L3MBTL1RAB9A | |
| SCHEMBL94347 | 0.80 | ALDH1A1 (0.55) | HTTALDH1A1MAPK1L3MBTL1RAB9A | |
| SCHEMBL2299040 | 0.80 | IDO1 (0.58) | HTTALDH1A1AKR1C3MAPK1L3MBTL1 | |
| SCHEMBL87044 | 0.80 | POLB (0.61) | HTTALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL3044366 | 0.80 | HTT (0.48) | HTTALDH1A1MAPK1L3MBTL1RAB9A | |
| SCHEMBL8867506 | 0.79 | TSHR (0.60) | HTTALDH1A1MAPK1L3MBTL1RAB9A | |
| SCHEMBL10639177 | 0.79 | MEN1 (0.63) | HTTALDH1A1MAPK1L3MBTL1RAB9A | |
| SCHEMBL8867503 | 0.79 | ALDH1A1 (0.54) | HTTALDH1A1MAPK1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4319028-A | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |