Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.59 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227235 | 1.00 | TLR8 (0.59) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL28046693 | 0.98 | TLR8 (0.61) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL6661787 | 0.96 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL5010709 | 0.96 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL15345465 | 0.91 | TLR8 (0.55) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL15345579 | 0.91 | TLR8 (0.55) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL5749320 | 0.89 | TLR8 (0.50) | TLR8LIPGMAPTMEN1TP53 | |
| SCHEMBL19583386 | 0.87 | TLR8 (0.56) | TLR8LIPGMEN1CYP3A4TYR | |
| Ammonia Solution, Strong SCHEMBL27937817 | 0.87 | TLR8 (0.51) | TLR8LIPGKCNH2MAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL27937828 | 0.87 | TLR8 (0.51) | TLR8LIPGKCNH2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360514-A | MOUTHWASHES, DENTIFRICES; ORAL DISEASES; CHEWING GUM; ANTIDEPOSIT AGENTS | JOHNSON & JOHNSON PRODUCTS INC. (US) | 1982-11-23 | — | — | US | disclosed |