Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.56 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010709 | 1.00 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL11229645 | 0.96 | TLR8 (0.59) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL11227235 | 0.96 | TLR8 (0.59) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL28046693 | 0.94 | TLR8 (0.61) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL19583386 | 0.92 | TLR8 (0.56) | TLR8LIPGMEN1KMT2ACYP3A4 | |
| SCHEMBL3110488 | 0.89 | ALOX5 (0.48) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL5749320 | 0.89 | TLR8 (0.50) | TLR8LIPGMAPTMEN1KMT2A | |
| SCHEMBL5749955 | 0.88 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL5745473 | 0.88 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 | |
| SCHEMBL5749346 | 0.88 | TLR8 (0.56) | TLR8LIPGKCNH2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433211-A2 | SUBSTITUTED PENTACENE SEMICONDUCTORS | 3M Innovative Properties Company (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028125-A2 | SUBSTITUTED PENTACENE SEMICONDUCTORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |