Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388795 | 0.81 | KDM4E (0.45) | HSD17B3MAOBACHEKDM4EALDH1A1 | |
| SCHEMBL5898250 | 0.80 | HSD17B3 (0.50) | SRCHSD17B3MAOBACHEKDM4E | |
| SCHEMBL27174640 | 0.80 | HSD17B3 (0.43) | SRCHSD17B3MAOBACHEKDM4E | |
| SCHEMBL6907581 | 0.78 | HSD17B3 (0.75) | HSD17B3MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL31138097 | 0.77 | AKR1B1 (0.48) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL961541 | 0.76 | HSD17B3 (0.73) | HSD17B3MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL25197790 | 0.76 | KDM4E (0.42) | SRCHSD17B3ACHEKDM4EALDH1A1 | |
| SCHEMBL15842733 | 0.76 | ESR2 (0.45) | SRCHSD17B3KDM4EALDH1A1HPGD | |
| SCHEMBL14408377 | 0.75 | ERAP1 (0.44) | SRCMAOBACHEKDM4EALDH1A1 | |
| SCHEMBL27920451 | 0.74 | ACHE (0.41) | SRCHSD17B3MAOBACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309353-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4205082-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |