Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 11/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454828 | 0.82 | POLB (0.51) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29010702 | 0.78 | CES1 (0.53) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11240815 | 0.77 | TLR9 (0.39) | TLR9MGLLGSK3BALDH1A1PARP1 | |
| SCHEMBL19511338 | 0.77 | TLR9 (0.58) | TLR9MGLLALDH1A1FAAHMEN1 | |
| SCHEMBL28465394 | 0.76 | MEN1 (0.56) | TLR9MGLLGSK3BKDM4EALDH1A1 | |
| SCHEMBL28883466 | 0.74 | TLR9 (0.54) | TLR9MGLLKDM4EALDH1A1HPGD | |
| SCHEMBL30000220 | 0.74 | TLR9 (0.54) | TLR9MGLLKDM4EALDH1A1HPGD | |
| SCHEMBL16754925 | 0.74 | GSK3B (0.62) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11230760 | 0.73 | TLR9 (0.52) | TLR9MGLLALDH1A1FAAHNPSR1 | |
| SCHEMBL28522247 | 0.72 | MAPT (0.57) | TLR9GSK3BKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365068-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4280946-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
| US-4219481-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4126619-A | CROSSLINKABLE BIS-IMIDYL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |