SCHEMBL11230760

SCHEMBL11230760

O=C1OC(=O)c2c1cccc2N1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.52
MGLL Q99685 14/20 0.50
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 1/20 0.41
FAAH O00519 4/20 0.41
TYMS P04818 2/20 0.39
ALDH1A1 P00352 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.38
CCR6 P51684 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516791 0.80 TDP1 (0.40) TDP1ALOX15TYMSALDH1A1
SCHEMBL10934363 0.79 KMT2A (0.41) TDP1ALOX15TYMS
SCHEMBL11517347 0.79 MEN1 (0.41) TDP1ALOX15TYMSALDH1A1PKM
SCHEMBL9596870 0.79 TLR9 (0.44) TLR9MGLLTDP1ALOX15FAAH
SCHEMBL19511338 0.79 TLR9 (0.58) TLR9MGLLTDP1FAAHALDH1A1
SCHEMBL11514963 0.77 KMT2A (0.43) TDP1ALOX15TYMSALDH1A1
SCHEMBL11510204 0.77 KMT2A (0.35) MGLLTDP1ALOX15TYMSALDH1A1
SCHEMBL30000220 0.76 TLR9 (0.54) TLR9MGLLTDP1ALOX15FAAH
SCHEMBL28883466 0.76 TLR9 (0.54) TLR9MGLLTDP1ALOX15FAAH
SCHEMBL11449701 0.75 MGLL (0.41) TLR9MGLLFAAHALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4365068-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1982-12-21 US disclosed
US-4365068-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1982-12-21 US disclosed
US-4280946-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1981-07-28 US disclosed
US-4280946-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1981-07-28 US disclosed
US-4219481-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4219481-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4160081-A Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins CIBA-GEIGY CORPORATION (US) 1979-07-03 US disclosed
US-4158662-A STORAGE STABLE MOLDING MATERIAL CIBA-GEIGY CORPORATION (US) 1979-06-19 US disclosed
US-4131613-A CURING AGENTS FOR EPOXIDE RESINS CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-4127712-A Phthalic acid diesters or ester-amides substituted by alkenylamino groups CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed
US-4126619-A CROSSLINKABLE BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-4126619-A CROSSLINKABLE BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-4115231-A Crosslinkable mixtures of oligomers or polymers and diamines CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4110188-A CROSSLINKABLE MIXTURES OF BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4110188-A CROSSLINKABLE MIXTURES OF BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-3979393-A Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed