Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389876 | 0.86 | HTR2A (0.55) | RETHTR2AOPRM1ACP3 | |
| Hydrochloric Acid SCHEMBL10743675 | 0.85 | HTR2A (0.53) | RETHTR2AOPRM1ACP3 | |
| SCHEMBL9245535 | 0.83 | HTR2A (0.46) | RETHTR2AFFAR1HSD17B3ACP3 | |
| Hydrochloric Acid SCHEMBL9247364 | 0.82 | RET (0.45) | RETHTR2AFFAR1HSD17B3 | |
| SCHEMBL14407922 | 0.76 | HTR2A (0.55) | HTR2A | |
| SCHEMBL7597435 | 0.76 | HTR2A (0.45) | MEN1KMT2ARETHTR2AOPRM1 | |
| SCHEMBL10962986 | 0.76 | HTR2A (0.41) | RETHTR2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11832796 | 0.76 | MAPT (0.56) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL11227753 | 0.75 | HTR2A (0.41) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL10743668 | 0.75 | HTR2A (0.53) | RETHTR2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346090-A | 13-Chloro-benzocycloheptapyridoisoquinolines and use as neuroleptics | AYERST, MCKENNA & HARRISON LTD. (CA) | 1982-08-24 | — | — | US | disclosed |