Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 3/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702813 | 0.83 | FUT8 (0.50) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL11224616 | 0.83 | APEX1 (0.49) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL30528721 | 0.83 | FUT8 (0.50) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL9233802 | 0.83 | FUT8 (0.53) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL10713192 | 0.81 | APEX1 (0.49) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL9283897 | 0.80 | APEX1 (0.46) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL19004055 | 0.78 | APEX1 (0.44) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL16560637 | 0.76 | APEX1 (0.46) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL10174724 | 0.76 | APEX1 (0.43) | APEX1NT5EPRMT1CYP2C9ALDH1A1 | |
| SCHEMBL16560636 | 0.76 | FUT8 (0.54) | APEX1NT5EPRMT1CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361698-A | Process for the manufacture of dihalogenotriazinylamino-naphthol compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-30 | — | — | US | disclosed |
| EP-0036133-A2 | Process for the preparation of dihalotriazinyl-amino-naphthol compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |