SCHEMBL19004055

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11224616	0.91	APEX1 (0.49)	APEX1NT5EPRMT1ALDH1A1CYP2C9
	SCHEMBL16560637	0.83	APEX1 (0.46)	APEX1NT5EPRMT1ALDH1A1CYP2C9
	SCHEMBL10174724	0.83	APEX1 (0.43)	APEX1NT5EPRMT1ALDH1A1CYP2C9
	SCHEMBL16560634	0.82	APEX1 (0.53)	APEX1NT5EALDH1A1CYP2C9CYP2C19
	SCHEMBL16560638	0.81	APEX1 (0.49)	APEX1NT5EPRMT1ALDH1A1CYP2C9
	SCHEMBL10938751	0.81	APEX1 (0.46)	APEX1NT5EALDH1A1CYP2C9CYP2C19
	SCHEMBL14087146	0.80	CA12 (0.39)	APEX1ALDH1A1CYP2C9CYP2C19HSD17B10
	SCHEMBL16557824	0.79	APEX1 (0.43)	APEX1NT5EPRMT1ALDH1A1CYP2C9
	SCHEMBL7753503	0.78	CA12 (0.45)	APEX1MEN1KMT2ACA12CA1
	SCHEMBL11230352	0.78	APEX1 (0.49)	APEX1NT5EPRMT1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.