Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456776 | 0.95 | THRB (0.53) | THRBPPARAPPARGHDAC1HDAC6 | |
| SCHEMBL2724431 | 0.93 | THRB (0.68) | THRBPPARAPPARGTHRA | |
| SCHEMBL23392587 | 0.93 | THRB (0.68) | THRBPPARAPPARGTHRA | |
| SCHEMBL15995743 | 0.93 | THRB (0.68) | THRBPPARAPPARGTHRA | |
| SCHEMBL19456770 | 0.89 | THRB (0.59) | THRBPPARAPPARGHDAC1HDAC6 | |
| SCHEMBL1401869 | 0.86 | THRB (0.67) | THRBPPARAPPARGTHRAACHE | |
| SCHEMBL11511884 | 0.84 | FFAR1 (0.51) | THRB | |
| SCHEMBL22195192 | 0.84 | THRB (0.56) | THRBACHE | |
| SCHEMBL19456881 | 0.83 | THRB (0.58) | THRBPPARAPPARGHDAC1HDAC6 | |
| SCHEMBL819501 | 0.82 | THRB (0.53) | THRBTHRAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320144-A | Fungicidal use of diphenyl esters of alkylenes | GAF CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |