Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654238 | 0.74 | PPARG (0.46) | PPARAALDH1A1LMNAHDAC1HDAC2 | |
| SCHEMBL11825284 | 0.69 | PPARA (0.41) | PPARAMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL7507755 | 0.69 | PPARG (0.39) | PPARAALDH1A1L3MBTL1HDAC1HDAC2 | |
| SCHEMBL5718637 | 0.69 | PPARA (0.43) | PPARAALDH1A1L3MBTL1PPARG | |
| SCHEMBL29564565 | 0.68 | PPARG (0.41) | PPARAMEN1KMT2AL3MBTL1HDAC1 | |
| SCHEMBL28154413 | 0.68 | ELANE (0.45) | PPARAL3MBTL1 | |
| SCHEMBL9417313 | 0.67 | PPARA (0.53) | PPARAMEN1KMT2APPARG | |
| SCHEMBL7604048 | 0.67 | KEAP1 (0.34) | PPARAHDAC1HDAC2 | |
| SCHEMBL11658502 | 0.66 | PPARA (0.37) | PPARAALDH1A1L3MBTL1PPARG | |
| SCHEMBL11658505 | 0.66 | PPARA (0.37) | PPARAALDH1A1L3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046532-B1 | 3,3-DIMETHYL-1-FLUORO-1-PHENOXY-2-BUTANONES(OLS), PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1983-09-14 | — | — | EP | claimed |
| EP-0046532-A1 | 3,3-Dimethyl-1-fluoro-1-phenoxy-2-butanones(ols), process for their preparation and their use | BAYER AG (DE) | 1982-03-03 | — | — | EP | disclosed |