Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15628136 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2 | |
| SCHEMBL22268953 | 0.71 | EPHX1 (0.36) | EPHX1HIF1A | |
| SCHEMBL28474947 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2 | |
| SCHEMBL18245282 | 0.70 | GABRA1 (0.63) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL959801 | 0.69 | GABRA1 (0.44) | HIF1AGABRA1GABRB2 | |
| SCHEMBL2049503 | 0.67 | EPHX1 (0.58) | EPHX1HIF1AALDH1A1 | |
| SCHEMBL10453742 | 0.66 | EPHX1 (0.52) | EPHX1HIF1AALDH1A1 | |
| SCHEMBL28423050 | 0.66 | EPHX1 (0.42) | EPHX1HIF1AALDH1A1 | |
| SCHEMBL1177299 | 0.65 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1 | |
| SCHEMBL27738631 | 0.64 | EPHX1 (0.54) | EPHX1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318924-A | Combating bacteria with N-cycloalkyl-N'-substituted-N'-acyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| EP-0019156-A1 | Substituted ureas, process for their preparation and phytobactericidal use of the same | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |