Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660470 | 0.92 | MRGPRX4 (0.62) | NR4A2MAOBMRGPRX4RXFP1 | |
| SCHEMBL1123502 | 0.84 | SMN1; SMN2 (0.61) | MAOBSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1123418 | 0.84 | NR1H4 (0.65) | MAOBSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL8148879 | 0.84 | NR1H4 (0.71) | NR4A2MAOBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1123220 | 0.83 | NPC1 (0.60) | MAOBSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1123360 | 0.83 | KDM4E (0.62) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL25426801 | 0.81 | BRD4 (0.67) | NR4A2MAOBMRGPRX4FFAR4RXFP1 | |
| SCHEMBL29824416 | 0.81 | BRD4 (0.67) | NR4A2MAOBMRGPRX4FFAR4RXFP1 | |
| SCHEMBL4206544 | 0.81 | NR4A2 (0.64) | NR4A2MAOBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1123139 | 0.80 | NPC1 (0.74) | MAOBSMN1; SMN2NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |