Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123360 | 0.88 | KDM4E (0.62) | NR1H4SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1123502 | 0.87 | SMN1; SMN2 (0.61) | NR1H4SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1122992 | 0.84 | SMN1; SMN2 (0.61) | NR1H4SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1123090 | 0.84 | NR4A2 (0.65) | NR1H4SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1123323 | 0.83 | PLK1 (0.64) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL1123501 | 0.82 | L3MBTL1 (0.63) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL38660185 | 0.82 | BRD4 (0.70) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL11549645 | 0.82 | BRD4 (0.70) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL5936652 | 0.81 | NPC1 (0.62) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 | |
| SCHEMBL1123096 | 0.81 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9ACASP3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |