SCHEMBL11230902

SCHEMBL11230902

ON=C(Cn1cnnc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
DRD4 P21917 3/20 0.39
CYP19A1 P11511 4/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
ATM Q13315 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TBXA2R P21731 3/20 0.37
PLAA Q9Y263 1/20 0.37
ALPG P10696 1/20 0.36
HTT P42858 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11230898 1.00 SMN1; SMN2 (0.41) SMN1; SMN2DRD4CYP19A1ESR1ESR2
SCHEMBL9218248 0.80 TBXA2R (0.57) CYP19A1ESR1ESR2ALDH1A1MAPT
SCHEMBL11229822 0.80 TBXA2R (0.57) CYP19A1ESR1ESR2ALDH1A1MAPT
SCHEMBL9218240 0.80 TBXA2R (0.57) CYP19A1ESR1ESR2ALDH1A1MAPT
SCHEMBL30461031 0.76 HMOX1 (0.49) SMN1; SMN2DRD4ATMALDH1A1NPSR1
SCHEMBL11236728 0.73 CYP19A1 (0.56) CYP19A1
SCHEMBL9790084 0.73 CYP19A1 (0.56) SMN1; SMN2CYP19A1ESR1ESR2MAPT
SCHEMBL30461053 0.73 POLB (0.41) DRD4ATMALDH1A1HPGDHTT
SCHEMBL9790080 0.73 CYP19A1 (0.56) SMN1; SMN2CYP19A1ESR1ESR2MAPT
SCHEMBL11236730 0.73 CYP19A1 (0.56) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed