Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233564 | 1.00 | KMT2A (0.35) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11235139 | 0.88 | KDM4E (0.38) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11235144 | 0.88 | KDM4E (0.38) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11238219 | 0.87 | KMT2A (0.43) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11238223 | 0.87 | KMT2A (0.43) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11339400 | 0.86 | KMT2A (0.34) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11339404 | 0.86 | KMT2A (0.34) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11247996 | 0.86 | KMT2A (0.36) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11248001 | 0.86 | KMT2A (0.36) | KMT2AKDM4EALDH1A1ATMCYP2C19 | |
| SCHEMBL11238962 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344953-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0005249-B1 | SUBSTITUTED ALKANYL-AZOLYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES, ACARICIDES AND NEMATOCIDES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |