Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231998 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HRH3KCNH2CCR2KCNA3 | |
| SCHEMBL2912511 | 0.78 | ALDH1A1 (0.82) | ALDH1A1HRH3KCNH2SLC6A4CCR2 | |
| SCHEMBL9803992 | 0.77 | CYP19A1 (0.43) | HRH3NISCH | |
| SCHEMBL955915 | 0.76 | NISCH (0.47) | ALDH1A1NISCH | |
| SCHEMBL14198375 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HRH3KDM4EMAPK1MAPT | |
| SCHEMBL14559342 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HRH3KDM4EMAPK1MAPT | |
| SCHEMBL14960094 | 0.70 | HRH3 (0.53) | ALDH1A1HRH3KDM4EHRH1 | |
| SCHEMBL20382562 | 0.70 | HRH3 (0.53) | ALDH1A1HRH3KDM4EHRH1 | |
| SCHEMBL3170537 | 0.69 | NISCH (0.53) | ALDH1A1NISCH | |
| SCHEMBL697119 | 0.68 | NISCH (0.52) | ALDH1A1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324792-A | SKIN DISORDERS, HAY FEVER, ASTHMA | GLAXO GROUP LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |