Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.52 |
| ▸ | CALML3 | P27482 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482868 | 0.88 | GRM2 (0.50) | MAOAMAOBGRM2CALML3SIGMAR1 | |
| SCHEMBL9482871 | 0.88 | GRM2 (0.50) | MAOAMAOBGRM2CALML3SIGMAR1 | |
| SCHEMBL9482719 | 0.83 | GRM2 (0.51) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL9482721 | 0.83 | GRM2 (0.51) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL1223001 | 0.83 | GRM2 (0.67) | MAOAMAOBGRM2SIGMAR1 | |
| SCHEMBL1223003 | 0.83 | GRM2 (0.67) | MAOAMAOBGRM2SIGMAR1 | |
| SCHEMBL9482693 | 0.81 | GRM2 (0.53) | MAOAMAOBGRM2CALML3SIGMAR1 | |
| SCHEMBL9484141 | 0.81 | GRM2 (0.53) | MAOAMAOBGRM2CALML3SIGMAR1 | |
| SCHEMBL9482678 | 0.81 | GRM2 (0.53) | MAOAMAOBGRM2CALML3SIGMAR1 | |
| SCHEMBL9484138 | 0.81 | GRM2 (0.53) | MAOAMAOBGRM2CALML3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338451-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-07-06 | — | — | US | disclosed |