Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222730 | 0.87 | TP53 (0.39) | TP53CA12CA2FDPS | |
| SCHEMBL11227092 | 0.85 | TP53 (0.47) | TP53CA2FDPS | |
| SCHEMBL11221941 | 0.84 | TP53 (0.46) | TP53CA2FDPS | |
| SCHEMBL11223611 | 0.81 | — | — | |
| SCHEMBL11222231 | 0.80 | — | — | |
| SCHEMBL11222443 | 0.79 | — | — | |
| SCHEMBL11581549 | 0.77 | — | — | |
| SCHEMBL11395178 | 0.76 | TP53 (0.35) | TP53HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL1726872 | 0.74 | SMN1; SMN2 (0.48) | TP53HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL11232375 | 0.74 | ALDH1A1 (0.33) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208037-A | Intermediate for synthesizing fluopropyl thiazoline derivative | NISSAN CHEMICAL IND LTD (JP) | 1999-02-17 | — | — | CN | disclosed |
| CN-1037349-C | Fluoropropyl thiazoline derivative and herbicide | NISSAN CHEMICAL IND LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
| CN-1138331-A | Fluoropropyl thiazoline derivative and herbicide | NISSAN CHEMICAL IND LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| US-4327034-A | CHEMICAL INTERMEDIATE PREPARED FROM A SULFAMIC ACID HALIDE AND A HALOGEN COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| US-4096181-A | Substituted sulfamic acid halides | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3992444-A | BY REACTION OF A SULFAMIC ACID WITH AN ACID HALIDE | BASF AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |