SCHEMBL1123430

SCHEMBL1123430

Cc1nc2ccccc2nc1OCCOc1ccc(C(=O)N(CC(=O)O)Cc2cccc(OCc3ccccc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.49
PPARG P37231 8/20 0.49
SLC2A1 P11166 6/20 0.47
SLC2A4 P14672 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGES O14684 2/20 0.44
CYP2C9 P11712 3/20 0.44
KCNH2 Q12809 2/20 0.44
ALOX5 P09917 1/20 0.44
LTC4S Q16873 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122793 0.95 L3MBTL1 (0.47) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1123269 0.93 L3MBTL1 (0.50) PPARAPPARGL3MBTL1PTGESALOX5
SCHEMBL1122873 0.92 SLC2A1 (0.45) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1122770 0.91 SLC2A1 (0.46) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1123219 0.87 CYSLTR2 (0.45) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1123226 0.86 L3MBTL1 (0.43) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1123108 0.86 L3MBTL1 (0.45) PPARAPPARGSLC2A1SLC2A4L3MBTL1
SCHEMBL1122802 0.84 L3MBTL1 (0.47) PPARAPPARGL3MBTL1PTGESALOX5
SCHEMBL1123013 0.83 FFAR1 (0.58) SLC2A1SLC2A4PTGESALOX5LTC4S
SCHEMBL5720728 0.82 CYSLTR2 (0.45) PPARAPPARGSLC2A1SLC2A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP disclosed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG PPARA 2/4885PPARG 3/4885SLC2A1 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.