SCHEMBL11234312

SCHEMBL11234312

CC(C)(c1ccc(O)cc1)c1c(Cl)c(Cl)c(O)c(Br)c1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.48
ESR2 Q92731 10/20 0.48
CYP3A4 P08684 4/20 0.48
HPGD P15428 2/20 0.48
TSHR P16473 2/20 0.48
HSD17B10 Q99714 2/20 0.48
AR P10275 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
SHBG P04278 1/20 0.34
ALOX15 P16050 3/20 0.33
ALOX12 P18054 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551990 0.90 ESR1 (0.48) ESR1ESR2CYP3A4HPGDTSHR
SCHEMBL26947 0.84 ESR1 (0.58) ESR1ESR2CYP3A4HPGDTSHR
SCHEMBL25881 0.84 ESR1 (0.58) ESR1ESR2CYP3A4HPGDTSHR
Cesium SCHEMBL30136131 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
Bromide SCHEMBL30239808 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
Potassium SCHEMBL30136058 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
SCHEMBL30136074 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
Potassium SCHEMBL30894669 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
Ammonia Solution, Strong SCHEMBL30540302 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR
SCHEMBL30384659 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315078-A Flame retardant flexible polyurethane foam containing finely divided inorganic salt wherein a mold of said salt contains at least five moles of water THE UPJOHN COMPANY (US) 1982-02-09 US disclosed