Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 11/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ESRRG | P62508 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26947 | 0.98 | ESR1 (0.58) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Potassium SCHEMBL30894669 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL30540302 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL30136074 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Potassium SCHEMBL30136058 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL30384659 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Cesium SCHEMBL30136131 | 0.96 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL8057791 | 0.91 | ESR1 (0.50) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bicarbonate SCHEMBL29445829 | 0.91 | ESR1 (0.50) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Phenol SCHEMBL30211186 | 0.91 | ESR1 (0.58) | ESR1ESR2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110684267-B | Special flame-retardant synergistic functional master batch for styrene resin modification and preparation method thereof | 江苏万纳普新材料科技有限公司 | 2023-04-07 | — | — | CN | disclosed |