Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249855 | 0.85 | MEN1 (0.68) | MEN1KMT2AHTR1AHTR7DRD4 | |
| SCHEMBL11162539 | 0.85 | MEN1 (0.64) | MEN1KMT2AHTR1AHTR7HRH3 | |
| SCHEMBL11246278 | 0.82 | MEN1 (0.70) | MEN1KMT2ADRD4ALDH1A1HTT | |
| SCHEMBL3583983 | 0.81 | CYP2D6 (0.60) | MEN1KMT2AHTR7HRH3DRD4 | |
| SCHEMBL8796387 | 0.79 | KDM4E (0.64) | MEN1KMT2AHTR1AHTR7HRH3 | |
| SCHEMBL29531493 | 0.79 | KDM4E (0.64) | MEN1KMT2AHTR1AHTR7HRH3 | |
| SCHEMBL11248180 | 0.78 | MEN1 (0.62) | MEN1KMT2AHTR1AHTR7ALDH1A1 | |
| SCHEMBL11168057 | 0.78 | MEN1 (0.64) | MEN1KMT2AHTR1AHTR7DRD4 | |
| SCHEMBL14100151 | 0.77 | TMEM97 (0.72) | HTR1AHRH3ACHELTA4HALDH1A1 | |
| SCHEMBL10461660 | 0.77 | MEN1 (0.55) | MEN1KMT2AHTR1AHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348401-A | ANTIHISTAMINIC, ANTIEDEMIC, ANTIPHLOGISTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1982-09-07 | — | — | US | disclosed |