Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.69 |
| ▸ | PGR | P06401 | 7/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233710 | 0.93 | NR3C1 (0.67) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11244253 | 0.93 | NR3C1 (0.65) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11845299 | 0.93 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11233706 | 0.92 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL4550220 | 0.92 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL4550151 | 0.92 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL24581296 | 0.92 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11323834 | 0.92 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11323839 | 0.92 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL24581680 | 0.92 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310466-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4263289-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1981-04-21 | — | — | US | disclosed |