Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 5/20 | 0.36 |
| ▸ | RXRB | P28702 | 4/20 | 0.36 |
| ▸ | RXRG | P48443 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234604 | 1.00 | BCL2L1 (0.37) | BCL2L1BADRXRARXRBRXRG | |
| SCHEMBL11232494 | 1.00 | BCL2L1 (0.37) | BCL2L1BADRXRARXRBRXRG | |
| SCHEMBL11232500 | 1.00 | BCL2L1 (0.37) | BCL2L1BADRXRARXRBRXRG | |
| SCHEMBL11232498 | 1.00 | BCL2L1 (0.37) | BCL2L1BADRXRARXRBRXRG | |
| SCHEMBL6964699 | 0.81 | HTR1A (0.49) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6966923 | 0.80 | HTR1A (0.48) | HTR2CHTR2B | |
| Ifoxetine SCHEMBL13918626 | 0.77 | SLC6A2 (0.42) | HTR2CHTR2BCSF1RKDR | |
| Ifoxetine SCHEMBL3961263 | 0.77 | SLC6A2 (0.42) | HTR2CHTR2BCSF1RKDR | |
| Ifoxetine SCHEMBL3959131 | 0.77 | SLC6A2 (0.42) | HTR2CHTR2BCSF1RKDR | |
| Ifoxetine SCHEMBL119624 | 0.77 | SLC6A2 (0.42) | HTR2CHTR2BCSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |