Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.50 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123023 | 0.95 | MAOB (0.53) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123229 | 0.93 | SLC2A1 (0.55) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123421 | 0.90 | NPC1 (0.53) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1122636 | 0.88 | BCHE (0.50) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123118 | 0.87 | KMT2A (0.58) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123188 | 0.86 | SLC2A1 (0.52) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123585 | 0.85 | MAOB (0.51) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123406 | 0.84 | NR4A2 (0.56) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123556 | 0.83 | SLC2A1 (0.53) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123181 | 0.83 | LPAR1 (0.49) | KMT2ASLC2A1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |