Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123421 | 0.95 | NPC1 (0.53) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1123556 | 0.94 | SLC2A1 (0.53) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1122604 | 0.93 | SLC2A1 (0.52) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123188 | 0.91 | SLC2A1 (0.52) | NPC1LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1123023 | 0.90 | MAOB (0.53) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1122984 | 0.87 | NR4A2 (0.56) | MAOBKMT2APTGESNR4A2SLC2A1 | |
| SCHEMBL1123468 | 0.87 | KMT2A (0.54) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5720728 | 0.86 | CYSLTR2 (0.45) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1123467 | 0.85 | NPC1 (0.55) | MAOBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL27638160 | 0.85 | ALOX5 (0.52) | NPC1LMNARAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |