Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GALR2 | O43603 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031240 | 0.84 | KIT (0.58) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL30225432 | 0.84 | KIT (0.58) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL11235031 | 0.81 | MAPT (1.00) | MAPTSMN1; SMN2TSHRRXFP1LMNA | |
| SCHEMBL7063580 | 0.81 | KIT (0.47) | MAPTLMNAHTTMAPK1 | |
| SCHEMBL14181340 | 0.80 | MAPT (0.46) | MAPTSMN1; SMN2TSHRKDM4EALDH1A1 | |
| SCHEMBL5849617 | 0.80 | PDGFRB (0.49) | MAPTSMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL6755688 | 0.79 | HTT (0.47) | MAPTTSHRLMNAHTTMAPK1 | |
| SCHEMBL2273815 | 0.79 | MAPT (0.61) | MAPTSMN1; SMN2TSHRRXFP1LMNA | |
| SCHEMBL11237400 | 0.77 | TLR7 (0.48) | SMN1; SMN2TSHRKDM4EHTTALDH1A1 | |
| SCHEMBL29247552 | 0.76 | AKT1 (0.58) | MAPTSMN1; SMN2TSHRRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340730-A | N6 -Substituted adenosines | G. D. SEARLE & CO. (US) | 1982-07-20 | — | — | US | disclosed |