Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225432 | 1.00 | KIT (0.58) | KITMAP4K4MAPTCNR1CNR2 | |
| SCHEMBL1030946 | 0.86 | MAP4K4 (0.47) | KITMAP4K4MAPTMEN1KMT2A | |
| SCHEMBL11235006 | 0.84 | MAPT (0.69) | MAP4K4MAPTMEN1KMT2ATSHR | |
| SCHEMBL3876920 | 0.84 | KIT (0.45) | KITMAP4K4MAPTCNR1CNR2 | |
| SCHEMBL1031242 | 0.82 | MAPT (0.73) | KITMAPTTSHRLMNAL3MBTL1 | |
| SCHEMBL1748427 | 0.81 | BTK (0.58) | MAPTCNR1CNR2MEN1KMT2A | |
| SCHEMBL30945074 | 0.81 | KIT (0.64) | KITJAK3 | |
| SCHEMBL28367516 | 0.81 | KIT (0.64) | KITJAK3 | |
| SCHEMBL5849252 | 0.81 | KIT (0.56) | KITMAP4K4MAPTCNR1CNR2 | |
| SCHEMBL7063580 | 0.80 | KIT (0.47) | KITMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| EP-4143172-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | Syddansk Universitet (DK) | 2023-03-08 | — | — | EP | disclosed |
| CN-115720579-A | Antibacterial and antifungal pleuromutilin conjugates | 赛丹思科大学 | 2023-02-28 | — | — | CN | disclosed |
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |
| CN-108822110-B | Aromatic heterocycle-containing a, β -unsaturated ketone compound and preparation method and application thereof | 山东大学 | 2020-03-13 | — | — | CN | disclosed |
| EP-1067123-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| CN-100376573-C | Fused 1, 3-dihydro-imidazole ring compounds | EISAI CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| US-7115741-B2 | 4-thieno[2,3-D]pyrimidin-4-YL piperazine compounds | ALEXION PHARMACEUTICALS, INC. | 2006-10-03 | — | — | US | disclosed |
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | EISAI CO., LTD. (JP) | 2006-05-25 | — | — | US | disclosed |
| CN-1745080-A | 1,3-dihydroimidazole fused-ring compound | EISAI CO LTD (JP) | 2006-03-08 | — | — | CN | disclosed |
| EP-1568699-A1 | 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND | Eisai Co., Ltd. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | HDAC6, Q6ZSR9, MON2 | KIT 2254/4885MAP4K4 1981/4885MAPT 1485/4885 |
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | NR2C2, NR0B2, DPP4 | KIT 4046/4885MAP4K4 3017/4885MAPT 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.