Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249452 | 1.00 | CA12 (0.40) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11245334 | 0.98 | CA12 (0.38) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11244276 | 0.98 | CA12 (0.38) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11241674 | 0.98 | CA12 (0.38) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11235670 | 0.86 | METAP1 (0.38) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11250082 | 0.84 | METAP1 (0.37) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL11242751 | 0.83 | METAP1 (0.35) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL2438366 | 0.81 | CTSK (0.40) | CTSKCTSLCTSBCTSH | |
| SCHEMBL11516522 | 0.77 | METAP1 (0.41) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6702235 | 0.73 | CTSK (0.41) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361577-A | ANTIULCER AND LUTEOLYTIC AGENTS | CARLO ERBA - S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |
| US-4169145-A | ANTIULCER AGENTS, LUTEOLYTIC ABORTIFACIENTS, OXYTOCICS | CARLO ERBA S.P.A. (IT) | 1979-09-25 | — | — | US | disclosed |
| US-4035415-A | GASTROINTESTINAL DISORDERS | CARLO ERBA, S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |