Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247202 | 0.87 | SMN1; SMN2 (0.51) | PCTPSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL11242722 | 0.83 | GCGR (0.54) | PCTPTDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11236412 | 0.80 | TDP1 (0.57) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11141988 | 0.78 | GCGR (0.60) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| Chlorbenzuron SCHEMBL5177776 | 0.77 | GCGR (0.68) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11247921 | 0.76 | GCGR (0.59) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10729809 | 0.73 | TDP1 (0.51) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10705754 | 0.73 | GCGR (0.64) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8624438 | 0.73 | TDP1 (0.62) | PCTPTDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11238363 | 0.72 | NPC1 (0.54) | TDP1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |