Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235213 | 0.87 | PCTP (0.50) | SMN1; SMN2MAPTRAB9ANPC1MEN1 | |
| SCHEMBL11241566 | 0.80 | MAPT (0.51) | SMN1; SMN2MAPTTHRBRAB9ACYP1A2 | |
| SCHEMBL28196235 | 0.74 | HPGD (0.74) | SMN1; SMN2MAPTTHRBRAB9ANPC1 | |
| SCHEMBL11233908 | 0.74 | PNLIP (0.49) | SMN1; SMN2MAPTTHRBRAB9ACYP2C19 | |
| SCHEMBL11138342 | 0.71 | RAB9A (0.64) | SMN1; SMN2MAPTTHRBRAB9ANPC1 | |
| SCHEMBL11252234 | 0.70 | HPGD (0.49) | SMN1; SMN2MAPTTHRBRAB9ANPC1 | |
| SCHEMBL11135787 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTTHRBRAB9ANPC1 | |
| SCHEMBL11242722 | 0.70 | GCGR (0.54) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL11244542 | 0.70 | RAB9A (0.43) | SMN1; SMN2MAPTTHRBRAB9ANPC1 | |
| SCHEMBL28221148 | 0.69 | HPGD (0.69) | SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |