Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841323 | 0.87 | HDAC8 (0.42) | HDAC8HDAC6HDAC2PLAUCRBN | |
| SCHEMBL5098817 | 0.81 | NPC1 (0.50) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL9709462 | 0.80 | MEN1 (0.42) | MEN1LMNAKMT2AHPGDTSHR | |
| SCHEMBL9436947 | 0.80 | CTNNB1 (0.41) | HPGDTSHR | |
| SCHEMBL11215650 | 0.80 | ALDH1A1 (0.50) | MEN1GAAKMT2ATSHR | |
| SCHEMBL1826388 | 0.79 | HTR1B (0.48) | MEN1GAAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL2788305 | 0.79 | KDM4E (0.59) | HPGDSMN1; SMN2ROCK2NPC1RAB9A | |
| SCHEMBL5944024 | 0.78 | ALDH1A1 (0.33) | TSHRNPC1RAB9A | |
| SCHEMBL11320077 | 0.77 | CPT1B (0.38) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL8961620 | 0.74 | MEN1 (0.50) | MEN1LMNAKMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |