Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 11/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235263 | 1.00 | DRD2 (0.53) | DRD2MEN1KMT2ADRD4DRD3 | |
| SCHEMBL11242259 | 0.94 | DRD2 (0.54) | DRD2DRD4DRD3ABCC8 | |
| SCHEMBL11243730 | 0.94 | DRD2 (0.54) | DRD2DRD4DRD3ABCC8 | |
| SCHEMBL11244187 | 0.92 | DRD2 (0.53) | DRD2DRD4DRD3ABCC8 | |
| SCHEMBL11238538 | 0.92 | DRD2 (0.53) | DRD2DRD4DRD3ABCC8 | |
| SCHEMBL11243700 | 0.92 | DRD2 (0.63) | DRD2DRD4DRD3 | |
| SCHEMBL11237343 | 0.92 | DRD2 (0.63) | DRD2DRD4DRD3 | |
| SCHEMBL11232514 | 0.87 | DRD2 (0.70) | DRD2DRD4DRD3OPRK1 | |
| SCHEMBL11232518 | 0.87 | DRD2 (0.70) | DRD2DRD4DRD3OPRK1 | |
| SCHEMBL11240647 | 0.86 | DRD2 (0.52) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352802-A | DESALINATION OF SEA WATER | BEECHAM GROUP LIMITED (GB) | 1982-10-05 | — | — | US | claimed |
| EP-0041817-A1 | Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-12-16 | — | — | EP | claimed |
| US-4352802-A | DESALINATION OF SEA WATER | BEECHAM GROUP LIMITED (GB) | 1982-10-05 | — | — | US | disclosed |
| EP-0041817-A1 | Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-12-16 | — | — | EP | disclosed |