SCHEMBL11235384

SCHEMBL11235384

O=C(O)C1CNCCN1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.36
TSHR P16473 3/20 0.36
SLC6A11 P48066 3/20 0.36
SLC6A13 Q9NSD5 3/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CHRNB2 P17787 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
CHRNB3 Q05901 1/20 0.32
CHRNA6 Q15825 1/20 0.32
GABRA5 P31644 3/20 0.32
GABRB2 P47870 3/20 0.32
GABRA1 P14867 2/20 0.32
GABRA4 P48169 2/20 0.32
PMP22 Q01453 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27701676 0.80 SLC6A1 (0.34) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL5892838 0.80 SLC6A1 (0.34) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL3272707 0.79 SLC6A1 (0.36) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL15542301 0.79 SLC6A1 (0.36) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL4383814 0.79 SLC6A1 (0.36) SLC6A1TSHRSLC6A11SLC6A13LMNA
Hydrochloric Acid SCHEMBL27824226 0.79 SLC6A1 (0.33) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL7108631 0.77 SLC6A1 (0.32) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL7348922 0.76 ATM (0.43) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL29208026 0.75 SLC6A1 (0.36) SLC6A1TSHRSLC6A11SLC6A13LMNA
SCHEMBL2916820 0.75 SLC6A1 (0.36) SLC6A1TSHRSLC6A11SLC6A13LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4327034-A CHEMICAL INTERMEDIATE PREPARED FROM A SULFAMIC ACID HALIDE AND A HALOGEN COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1982-04-27 US disclosed