SLC6A1
Sodium- and chloride-dependent GABA transporter 1 · P30531 · SLC6A1 on Sugi Atlas →
22,784 patent compounds predicted against SLC6A1, 8,258 high-confidence (nearest known ligand ≥ 0.5)
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours | |
|---|---|---|---|
| SCHEMBL676997 | 1.00 | 15/20 | |
| SCHEMBL676998 | 1.00 | 15/20 | |
| Tiagabine (SCHEMBL34653) | 1.00 | 10/20 | |
| Tiagabine (SCHEMBL342814) | 1.00 | 10/20 | |
| Tiagabine (SCHEMBL677642) | 0.70 | 10/20 | |
| SCHEMBL262828 | 0.49 | 9/20 | |
| Tiagabine (SCHEMBL41860) | 1.00 | 8/20 | |
| Tiagabine (SCHEMBL1462478) | 0.57 | 8/20 | |
| Ticarcillin (SCHEMBL1462788) | 0.54 | 8/20 | |
| SCHEMBL262183 | 0.45 | 5/20 | |
| SCHEMBL1225755 | 0.77 | 4/20 | |
| SCHEMBL44023 | 0.69 | 4/20 | |
| SCHEMBL45098 | 0.57 | 4/20 | |
| SCHEMBL1249676 | 0.57 | 4/20 | |
| SCHEMBL1249678 | 0.57 | 4/20 | |
| SCHEMBL1249680 | 0.57 | 4/20 | |
| SCHEMBL1251294 | 0.57 | 4/20 | |
| SCHEMBL1251296 | 0.57 | 4/20 | |
| SCHEMBL764125 | 0.52 | 4/20 | |
| SCHEMBL40181 | 0.50 | 4/20 |
Clinical trials — most relevant to SLC6A1 by text similarity (a relevance ranking, not an exhaustive list)
Related proteins — ESM-2 sequence neighbours (a SLC6A1 binder may also engage these)
| Protein | Name | Similarity | |
|---|---|---|---|
| P48057 | — | 1.000 | P48057 → |
| SLC6A13 | Sodium- and chloride-dependent GABA transporter 2 | 1.000 | landscape → |
| B4JMC1 | — | 1.000 | B4JMC1 → |
| Q9MZ34 | — | 1.000 | Q9MZ34 → |
| P31650 | — | 1.000 | P31650 → |
| P51905 | — | 1.000 | P51905 → |
| Q00589 | — | 1.000 | Q00589 → |
| Q9JMA9 | — | 1.000 | Q9JMA9 → |
| Q9XT49 | — | 1.000 | Q9XT49 → |
| Q8VDB9 | — | 1.000 | Q8VDB9 → |
| Q7K4Y6 | — | 1.000 | Q7K4Y6 → |
| Q28039 | — | 1.000 | Q28039 → |
| Q8VBW1 | — | 1.000 | Q8VBW1 → |
| SLC6A3 | Sodium-dependent dopamine transporter | 0.999 | landscape → |
| P31649 | — | 0.999 | P31649 → |
| Q9W4C5 | — | 0.999 | Q9W4C5 → |
| P31646 | — | 0.998 | P31646 → |
| SLC6A4 | Sodium-dependent serotonin transporter | 0.998 | landscape → |
| B4MEG2 | — | 0.998 | B4MEG2 → |
| O35899 | — | 0.998 | O35899 → |
| SLC6A12 | Sodium- and chloride-dependent betaine transporter | 0.997 | landscape → |
| Q29GB8 | — | 0.997 | Q29GB8 → |
| SLC6A11 | Sodium- and chloride-dependent GABA transporter 3 | 0.997 | landscape → |
| Q2A865 | — | 0.997 | Q2A865 → |
| P23978 | — | 0.997 | P23978 → |
| P51143 | — | 0.996 | P51143 → |
| Q9MYX0 | — | 0.996 | Q9MYX0 → |
| P31648 | — | 0.996 | P31648 → |
| P31652 | — | 0.996 | P31652 → |
| SLC6A6 | Sodium- and chloride-dependent taurine transporter | 0.996 | landscape → |