Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27293026 | 0.86 | NOS3 (0.50) | CYP2C9NOS3NOS1NOS2ALPI | |
| SCHEMBL27293020 | 0.86 | NOS3 (0.50) | CYP2C9NOS3NOS1NOS2ALPI | |
| SCHEMBL9543040 | 0.83 | KMT2A (0.42) | NOS3NOS1NOS2LTA4HANPEP | |
| SCHEMBL27296261 | 0.83 | KMT2A (0.42) | NOS3NOS1NOS2LTA4HANPEP | |
| Hydrochloric Acid SCHEMBL27327728 | 0.82 | KMT2A (0.41) | NOS3NOS1NOS2LTA4HANPEP | |
| SCHEMBL27624205 | 0.82 | MEN1 (0.43) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL27327731 | 0.82 | KMT2A (0.41) | NOS3NOS1NOS2LTA4HANPEP | |
| SCHEMBL27624203 | 0.82 | MEN1 (0.43) | NOS3NOS1NOS2 | |
| Phenylalanine SCHEMBL27624223 | 0.81 | SLC7A5 (0.61) | SLC6A3NOS3NOS1NOS2LTA4H | |
| Dl-Phenylalanine SCHEMBL28207394 | 0.81 | SLC7A5 (0.61) | SLC6A3NOS3NOS1NOS2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338346-A | Non-nutritive sweetener | THE PROCTER & GAMBLE COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0013044-A1 | L-aspartyl amide derivatives and their use as sweetening agents | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |