Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235832 | 1.00 | GABRR1 (0.32) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11228740 | 0.83 | GABRR1 (0.44) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11237630 | 0.83 | GABRR1 (0.44) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL13083468 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL21609283 | 0.73 | LMNA (0.35) | LMNATSHR | |
| Hydrochloric Acid SCHEMBL6853864 | 0.72 | CYP2C19 (0.42) | BLMLMNAAPEX1 | |
| Hydrochloric Acid SCHEMBL6853860 | 0.72 | CYP2C19 (0.42) | BLMLMNAAPEX1 | |
| SCHEMBL23534726 | 0.71 | BLM (0.37) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL22558365 | 0.71 | BLM (0.37) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11239601 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323704-A | ENZYME INHIBITORS USEFUL AGAINST BACTERIA, FUNGUS AND VIRAL INFECTIONS, MALE ANTIFERTILITY AGENTS, IMMUNO-SUPPRESSANTS, AND ANTITUMOR ACTIVITY | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-04-06 | — | — | US | disclosed |
| US-4267374-A | BACTERICIDES; VIRICIDES; FUNGICIDES; INHIBITORS OF HYDROLASE ENZYMES; INTERMEDIATE FOR CEPHALOSPORIN COMPOUND | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-05-12 | — | — | US | disclosed |