Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235857 | 1.00 | PTGS1 (0.85) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL11045643 | 0.95 | PTGS1 (0.77) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL11115278 | 0.95 | PTGS1 (0.77) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL11045641 | 0.95 | PTGS1 (0.77) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL11115279 | 0.95 | PTGS1 (0.77) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11149195 | 0.94 | PTGS1 (0.75) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11150123 | 0.94 | PTGS1 (0.75) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Cephaloglycin SCHEMBL10703211 | 0.92 | PTGS1 (1.00) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Cephaloglycin SCHEMBL2947 | 0.92 | PTGS1 (1.00) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Cephaloglycin SCHEMBL11635199 | 0.92 | PTGS1 (1.00) | PTGS1ALDH1A1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4319028-A | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4145538-A | 3-Carbamyloxymethyl-cephalosporins | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4061630-A | 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |