Cephaloglycin

Cephaloglycin

SCHEMBL2947

CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Cephaloglycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 1.00
▸ L3MBTL1 Q9Y468 2/20 0.73
▸ TDP1 Q9NUW8 5/20 0.71
▸ MAPT P10636 7/20 0.70
▸ ALDH1A1 P00352 6/20 0.70
▸ HSD17B10 Q99714 6/20 0.70
▸ HPGD P15428 4/20 0.70
▸ KMT2A Q03164 4/20 0.70
▸ CYP3A4 P08684 3/20 0.70
▸ SLC15A2 Q16348 3/20 0.70
▸ BLM P54132 1/20 0.70
▸ CYP2C19 P33261 1/20 0.70
▸ MAPK1 P28482 1/20 0.70
▸ ADRA1A P35348 1/20 0.70
▸ HTR2B P41595 1/20 0.70
▸ KDM4E B2RXH2 4/20 0.67
▸ MEN1 O00255 3/20 0.67
▸ NR1I2 O75469 3/20 0.67
▸ CYP2C9 P11712 2/20 0.67
▸ CTDSP1 Q9GZU7 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cephaloglycin SCHEMBL11419396 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL6154818 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL11742799 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL11278573 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL16072815 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL11635204 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL10703211 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL11222714 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL11635199 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1
Cephaloglycin SCHEMBL8480395 1.00 PTGS1 (1.00) PTGS1L3MBTL1TDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8574 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637481-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2026-05-26 — — US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 — — US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 — — US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 — — US claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 — — EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 — — EP claimed
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 — — US claimed
US-20250222118-A1 Beta-Lactam-Cannabinoid Conjugate Molecules DIVERSE BIOTECH INC (US) 2025-07-10 — — US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 — — WO claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 — — US claimed
EP-0026409-A1 Combinations of active ingredients, pharmaceutical preparations, as well as their preparation F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-04-08 — — EP claimed
US-4254029-A SILYLATION, AMIDATION WITH A PHENYLGLYCYL CHLORIDE HYDROCHLORIDE AND HYDROLYSIS TO PRODUCE PENICILLIN AND CEPHALOSPORIN DERIVATIVES PLANTEX LTD. (IL) 1981-03-03 — — US claimed
EP-0007717-A1 Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1980-02-06 — — EP claimed
EP-0004770-A2 Pharmaceutical and dietary composition comprising gamma-linolenic acids EFAMOL LIMITED (GB) 1979-10-17 — — EP claimed
US-4143134-A BACTERICIDES, ANTIBIOTIC POTENTIATORS HOFFMANN-LA ROCHE INC. (US) 1979-03-06 — — US claimed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 — — US claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 — — US claimed
US-4028355-A Cephalosporin purification process SMITHKLINE CORPORATION (US) 1977-06-07 — — US claimed
US-3937655-A Method for preparing stable β-lactam-type-antibiotic susceptibility test discs ELI LILLY AND COMPANY (US) 1976-02-10 — — US claimed
US-3931404-A High dosage orally administrable cephalosporin antibiotic preparations HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 — — US claimed
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