Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497768 | 0.90 | TSHR (0.48) | NPSR1TSHRGRM5APPRAB9A | |
| Benzonitrile SCHEMBL4165728 | 0.72 | TSHR (0.78) | TSHRAPPKMT2AALDH1A1MAPT | |
| Benzonitrile SCHEMBL4151051 | 0.72 | TSHR (0.78) | TSHRAPPKMT2AALDH1A1MAPT | |
| Benzonitrile SCHEMBL4156207 | 0.72 | TSHR (0.78) | TSHRAPPKMT2AALDH1A1MAPT | |
| Benzonitrile SCHEMBL4152939 | 0.72 | TSHR (0.78) | TSHRAPPKMT2AALDH1A1MAPT | |
| Benzonitrile SCHEMBL4154095 | 0.72 | TSHR (0.78) | TSHRAPPKMT2AALDH1A1MAPT | |
| Carbon Monoxide SCHEMBL9444669 | 0.71 | APP (0.47) | NPSR1TSHRGRM5APPRAB9A | |
| Trimethylammonium SCHEMBL27539624 | 0.67 | NPSR1 (0.45) | NPSR1TSHRGRM5APPRAB9A | |
| Carbon Monoxide SCHEMBL11121318 | 0.67 | ALDH1A1 (0.53) | TSHRRAB9ANPC1MEN1KMT2A | |
| Carbon Monoxide SCHEMBL11241410 | 0.67 | APP (0.38) | NPSR1TSHRGRM5APPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331559-A | Olefin disproportionation | PHILLIPS PETROLEUM COMPANY (US) | 1982-05-25 | — | — | US | claimed |
| US-4291187-A | USING A RHENIUM OR TUNGSTEN CARBENE CATALYST COMPLEX | PHILLIPS PETROLEUM COMPANY (US) | 1981-09-22 | — | — | US | disclosed |
| US-4262156-A | NEUTRAL METAL CARBENE CATALYST, HALOGENATED AND TIN PROMOTERS | PHILLIPS PETROLEUM CO. (US) | 1981-04-14 | — | — | US | disclosed |