Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659039 | 0.88 | NPC1 (0.47) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL10908649 | 0.86 | NPC1 (0.45) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL11250296 | 0.86 | KMT2A (0.43) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL11237302 | 0.85 | ATM (0.42) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL11244616 | 0.85 | ATM (0.42) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL11242054 | 0.85 | NPC1 (0.44) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL10906940 | 0.85 | NPC1 (0.44) | ATMNPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL10906894 | 0.83 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL11390176 | 0.83 | ATM (0.45) | ATMNPC1RAB9AKMT2APKM | |
| SCHEMBL11244282 | 0.81 | NPC1 (0.50) | NPC1RAB9AMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | claimed |
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |