Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388137 | 0.96 | ATM (0.42) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL10906894 | 0.92 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL10910904 | 0.91 | NPC1 (0.42) | NPC1RAB9AMAPTPKM | |
| SCHEMBL11243575 | 0.88 | FAAH (0.42) | — | |
| SCHEMBL8659039 | 0.85 | NPC1 (0.47) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL11235882 | 0.85 | ATM (0.46) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL10909648 | 0.85 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL10908649 | 0.83 | NPC1 (0.45) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL11240030 | 0.83 | ITGA4 (0.44) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL11242054 | 0.83 | NPC1 (0.44) | NPC1RAB9AATMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | claimed |
| US-4567295-A | Composition active against mites, whitefly and thrips, pharmaceutical composition, and new benzoylurea compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-01-28 | — | — | US | disclosed |
| EP-0116728-A1 | Composition active against mites, whitefly and thrips, pharmaceutical composition, and new benzoylureau compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |