Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.88 |
| ▸ | PGR | P06401 | 5/20 | 0.88 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.88 |
| ▸ | LMNA | P02545 | 4/20 | 0.88 |
| ▸ | AR | P10275 | 3/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.88 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.88 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.88 |
| ▸ | USP2 | O75604 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mometasone Furoate SCHEMBL2594997 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL600107 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL12996648 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL13026146 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL8430908 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL25382496 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL4896227 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL4568 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL7436523 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL8826257 | 0.93 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057401-A1 | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-08-11 | — | — | EP | disclosed |