SCHEMBL1123624

SCHEMBL1123624

CC(C)(Br)C(=O)Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.79
KDM4E B2RXH2 4/20 0.49
HSD17B10 Q99714 4/20 0.49
HPGD P15428 2/20 0.49
ALDH1A1 P00352 1/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
TSHR P16473 1/20 0.49
GGT1 P19440 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
BLM P54132 1/20 0.49
NAPRT Q6XQN6 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPT P10636 4/20 0.48
MAPK1 P28482 2/20 0.48
SLC6A3 Q01959 1/20 0.47
AKR1C3 P42330 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10483734 0.89 ELANE (1.00) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL10025684 0.85 KDM4E (0.62) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL825357 0.83 ELANE (0.73) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL5308300 0.81 KDM4E (0.72) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL14330484 0.79 ELANE (0.68) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL29358894 0.79 ELANE (0.67) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL3978408 0.79 ELANE (0.67) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL474967 0.79 ELANE (0.67) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL28741706 0.78 ELANE (0.66) ELANEKDM4EHSD17B10HPGDALDH1A1
SCHEMBL8589792 0.78 ELANE (0.64) ELANEKDM4EHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160326022-A1 FILTRATION MODULE TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2016-11-10 US disclosed
US-8871831-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2014-10-28 US disclosed
US-20140134445-A1 POLYMERIC CONTACT MEDIA Yaeger, Evelyn (US) 2014-05-15 US disclosed
US-20140058032-A1 MODIFICATION OF SURFACES WITH POLYMERS CARNEGIE MELLON UNIVERSITY 2014-02-27 US disclosed
US-20130244046-A1 POLYMERIC CONTACT MEDIA YAEGER, EVELYN 2013-09-19 US disclosed
US-20130131278-A1 MODIFICATION OF SURFACES WITH POLYMERS NATIONAL SCIENCE FOUNDATION 2013-05-23 US disclosed
US-8349410-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2013-01-08 US disclosed
EP-2464740-A1 STIMULI RESPONSIVE MEMBRANE Sensile Pat AG (CH) 2012-06-20 EP disclosed
US-20120150006-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2012-06-14 US disclosed
WO-2011018752-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2011-02-17 WO disclosed
EP-2284275-A1 Stimuli Responsive Membrane Sensile Pat AG (CH) 2011-02-16 EP disclosed
US-20080139689-A1 Controlled free radical polymerization, crosslinking, Norrish reaction; segments can be hydrophilicity, hydrophobicity, biocompatibility, bioactivity, adhesion, adsorption; corrosion, abrasion and, heat resistance; dielectrics; poly(3-(trimethoxysilyl)propyl methacrylate) segment; quaternized groups NATIONAL SCIENCE FOUNDATION 2008-06-12 US disclosed
WO-2008021500-A2 MODIFICATION OF SURFACES WITH POLYMERS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2008-02-21 WO disclosed