Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761136 | 0.82 | ELANE (0.73) | ELANEALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10483734 | 0.79 | ELANE (1.00) | ELANEALDH1A1SLC6A3KDM4EHPGD | |
| SCHEMBL1123624 | 0.78 | ELANE (0.79) | ELANEALDH1A1CYP2C9SLC6A3KDM4E | |
| SCHEMBL474832 | 0.76 | ELANE (0.58) | ELANEALDH1A1SLC6A3KDM4EHPGD | |
| SCHEMBL29805146 | 0.76 | ELANE (0.58) | ELANEALDH1A1SLC6A3KDM4EHPGD | |
| Benzophenone SCHEMBL27306900 | 0.75 | ELANE (0.56) | ELANEALDH1A1SLC6A3KDM4EHPGD | |
| SCHEMBL25765134 | 0.75 | ALDH1A1 (0.47) | ELANEALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL825357 | 0.74 | ELANE (0.73) | ELANEALDH1A1SLC6A3KDM4EHPGD | |
| SCHEMBL5308300 | 0.72 | KDM4E (0.72) | ELANEALDH1A1CYP2C9SLC6A3KDM4E | |
| SCHEMBL7932440 | 0.72 | ELANE (0.49) | ELANEALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773485-A | CURABLE MONOMERS FOR ACRYLATE POLYMERS FOR COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-06-30 | — | — | US | disclosed |