Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052799 | 0.82 | SLC6A2 (0.56) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL5403775 | 0.80 | SLC6A4 (0.54) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL8341049 | 0.80 | SLC6A4 (0.51) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| Oxalic Acid SCHEMBL7317717 | 0.76 | SLC6A2 (0.60) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL1045800 | 0.74 | SLC6A4 (0.71) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL5306302 | 0.74 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL2212613 | 0.74 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL7055148 | 0.74 | SLC6A2 (0.55) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL7053112 | 0.74 | SLC6A4 (0.70) | SLC6A2SLC6A4CYP2D6SLC6A3KCNK2 | |
| SCHEMBL4624371 | 0.74 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313896-A | ANTIDEPRESSANTS, PSYCHOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | claimed |