SCHEMBL11236337

SCHEMBL11236337

O=C=Nc1cccc(CCl)c1F

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17170062 0.85 CYP3A4 (0.47) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL28210896 0.82 CYP3A4 (0.60) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL29648904 0.80 CYP3A4 (0.48) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL93414 0.80 CYP3A4 (0.48) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL7723447 0.79 GABRA1 (0.55) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL9551403 0.79 CYP3A4 (0.48) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL11234939 0.79 GABRA1 (0.50) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL11870989 0.78 CYP3A4 (0.47) CYP3A4GABRA1GABRB2TSHRALDH1A1
SCHEMBL163526 0.77 CYP3A4 (0.50) CYP3A4GABRA1GABRB2ALDH1A1TRPA1
SCHEMBL10885416 0.76 CYP3A4 (0.46) CYP3A4GABRA1GABRB2ALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4331821-A ULTRAVIOLET RADIATION OF A VAPORIZED ALKYLBENZEN AND HALOGEN GAS MIXTURE BAYER AKTIENGESELLSCHAFT (DE) 1982-05-25 US disclosed