SCHEMBL1123655

SCHEMBL1123655

CC(Br)C(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
HSD17B10 Q99714 4/20 0.65
HIF1A Q16665 3/20 0.65
KDM4E B2RXH2 3/20 0.65
LMNA P02545 3/20 0.65
ALDH1A1 P00352 2/20 0.65
HPGD P15428 2/20 0.65
BLM P54132 2/20 0.65
PTGS1 P23219 1/20 0.65
GLI1 P08151 1/20 0.56
GLI2 P10070 1/20 0.56
ERCC1 P07992 2/20 0.55
ERCC4 Q92889 2/20 0.55
CYP1A2 P05177 2/20 0.54
TSHR P16473 2/20 0.54
NFKB1 P19838 2/20 0.54
MAPK1 P28482 2/20 0.54
THPO P40225 2/20 0.54
TP53 P04637 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31475411 1.00 MAPT (0.65) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL9965254 0.88 ERCC1 (0.71) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL5053837 0.86 MAPT (0.67) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL4949922 0.86 MAPT (0.67) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL22615896 0.85 MAPT (0.61) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL7364941 0.85 MAPT (0.65) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL28976208 0.85 MAPT (0.65) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL27269169 0.85 MAPT (0.65) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL30281537 0.85 MAPT (0.65) MAPTHSD17B10HIF1AKDM4ELMNA
SCHEMBL27272665 0.84 MAPT (0.63) MAPTHSD17B10HIF1AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060009550-A1 Polymeric compositions and related methods of use NIH - DEITR 2006-01-12 US claimed
US-10751896-B2 Shaving article with surface modification THE GILLETTE COMPANY LLC (US) 2020-08-25 US disclosed
US-10751896-B2 Shaving article with surface modification THE GILLETTE COMPANY LLC (US) 2020-08-25 US disclosed
US-20180236678-A1 SHAVING ARTICLE WITH SURFACE MODIFICATION THE GILLETTE COMPANY 2018-08-23 US disclosed
WO-2018151961-A1 SHAVING ARTICLE WITH SURFACE MODIFICATION THE GILLETTE COMPANY LLC (US) 2018-08-23 WO disclosed
EP-3363834-A1 SHAVING ARTICLE WITH SURFACE MODIFICATION The Gillette Company LLC (US) 2018-08-22 EP disclosed
EP-3363836-A1 SHAVING ARTICLE WITH SURFACE MODIFICATION The Gillette Company LLC (US) 2018-08-22 EP disclosed
WO-2018138677-A1 PROCESS FOR THE SYNTHESIS OF STIMULUS-RESPONSIVE MAGNETIC NANOPARTICLES FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2018-08-02 WO disclosed
US-8394022-B2 Selectively permeable coated membrane SENSILE PAT AG (CH) 2013-03-12 US disclosed
EP-2464740-A1 STIMULI RESPONSIVE MEMBRANE Sensile Pat AG (CH) 2012-06-20 EP disclosed
US-20120150006-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2012-06-14 US disclosed
WO-2011018752-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2011-02-17 WO disclosed
EP-2284275-A1 Stimuli Responsive Membrane Sensile Pat AG (CH) 2011-02-16 EP disclosed
US-7858679-B2 Polymeric compositions and related methods of use NORTHWESTERN UNIVERSITY (US) 2010-12-28 US disclosed
US-7858679-B2 Polymeric compositions and related methods of use NORTHWESTERN UNIVERSITY (US) 2010-12-28 US disclosed
EP-2055226-A1 Selectively permeable coated membrane Sensile Pat AG (CH) 2009-05-06 EP disclosed
US-20090112075-A1 SELECTIVELY PERMEABLE COATED MEMBRANE SENSILE MEDICAL AG (CH) 2009-04-30 US disclosed
WO-2008028206-A2 METHOD FOR PRODUCING REACTIVE MONOLAYER UNITS Universität Linz (AT) 2008-03-13 WO disclosed