Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.71 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | GLI1 | P08151 | 1/20 | 0.58 |
| ▸ | GLI2 | P10070 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949922 | 0.89 | MAPT (0.67) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL5053837 | 0.89 | MAPT (0.67) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL7364941 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL27269169 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL28976208 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL31475411 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL30281537 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL1123655 | 0.88 | MAPT (0.65) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL27272665 | 0.86 | MAPT (0.63) | ERCC1ERCC4MAPTHSD17B10HIF1A | |
| SCHEMBL17898047 | 0.85 | MAPT (0.61) | ERCC1ERCC4MAPTHSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072899-A2 | DISINFECTANT COMPOSITIONS AND METHODS THEREOF | HALOMINE INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20180169275-A1 | POLYMERIC MICELLAR NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-06-21 | — | — | US | disclosed |
| US-20160346424-A1 | ADHESIVE COMPOUNDS AND METHODS USE FOR HERNIA REPAIR | KNC NER ACQUISITION SUB, INC. | 2016-12-01 | — | — | US | disclosed |
| US-8916652-B2 | Multi-armed catechol compound blends | KENSEY NASH CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-8846839-B2 | Copolymers having zwitterionic moieties and dihdroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2014-09-30 | — | — | US | disclosed |
| US-8399584-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120157602-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | US | disclosed |
| US-8202956-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2012-06-19 | — | — | US | disclosed |
| US-8119742-B2 | Multi-armed catechol compound blends | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-8101156-B2 | Methods of manufacturing copolymers with zwitterionic moieties and dihydroxyphenyl moieties and use of same | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110166250-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHYDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110160382-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-7928176-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | NERITES CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| US-20080153923-A1 | Biocompatible polymer; copolymerize a dihydroxyphenyl monomer with acrylate comonomer to yield intermediate polymer; coupling zwitterionic phosphorylcholine to the acrylate comonomer of intermediate product to yield a thermoplastic polymer; improved adhesion to surface of implantable medical device | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | US | disclosed |
| US-20080139746-A1 | Polymer preferably includes methacryloyloxyethyl phosphorylcholine, and a cationic monomer, a monomer with a pendant hydrocarbon group or a monomer with a pendant hydrophilic group; blends with polyvinylpyrrolidone, a polyacrylate or terpolymer; improved adhesion, primers not needed; stent coatings | ABBOTT LABORATORIES (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | COMT, HAAO, PNMT | ERCC1 1920/4885ERCC4 1693/4885MAPT 909/4885 |
| US-20180169275-A1 | POLYMERIC MICELLAR NANOPARTICLES | PHOSPHO1, LIPA, PITPNB | ERCC1 2880/4885ERCC4 3650/4885MAPT 106/4885 |
| US-20080153923-A1 | Biocompatible polymer; copolymerize a dihydroxyphenyl monomer with acrylate comonomer to yield intermediate polymer; coupling zwitterionic phosphorylcholine to the acrylate comonomer of intermediate product to yield a thermoplastic polymer; improved adhesion to surface of implantable medical device | CAD, PHOSPHO1, CD14 | ERCC1 2017/4885ERCC4 3042/4885MAPT 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.